Disclosed herein are various polypeptides that can be included in immunog enic compositions specific for pathogenic E. coli strains. The polypeptides have cellular locations which render them accessible to the immune system. T he genes encoding the polypeptides were initially identified as being presen t in uropathogenic strain 536 but absent from non-pathogenic strains.</SDOAB >
申请公布号
CA2659552(A1)
申请公布日期
2008.02.21
申请号
CA20072659552
申请日期
2007.08.15
申请人
NOVARTIS AG
发明人
FONTANA, MARIA RITA;SERINO, LAURA;PIZZA, MARIAGRAZIA;HACKER, JOERG;MORIEL, DANILO GOMES;SCORZA, FRANCESCO BERLANDA