CRYSTALLINE ANTIFUNGAL COMPOUNDS

摘要

Novel crystalline forms of (1R,2R)-7-chloro-3-[2-(2,4-difluorophenyl)-2-h ydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin-4(3H)-one, pharma ceutical compositions containing these crystalline forms, methods of using t hese crystalline forms for treating and/or preventing various microbial and/ or fungal infections or disorders, and processes for obtaining these crystal line forms. In particular, the present subject matter relates to the specifi c crystalline Forms I, II, III, IV, V, and VI of (1R, 2R)-7-chloro-3-[2-(2,4 -difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazol in-4(3H)-one.