发明名称 PYRIMIDINE DERIVATIVE AS PI3K INHIBITOR AND USE THEREOF
摘要 Disclosed is a medical agent which is excellent in stability in living bodies and water solubility, while having excellent PI3K inhibitory activity. The medical agent is thus useful for prevention or treatment of cancers. Specifically disclosed is a compound represented by the formula (I) below or a pharmaceutically acceptable salt thereof. (I) (In the formula, X represents a single bond or the like; Y represents a single bond or the like (provided that X and Y are not single bonds at the same time); Z represents a hydrogen atom or the like; m represents an integer of 1 or 2; and R<SUP>1</SUP> represents a cyclic substituent.)
申请公布号 WO2008018426(A1) 申请公布日期 2008.02.14
申请号 WO2007JP65396 申请日期 2007.08.07
申请人 CHUGAI SEIYAKU KABUSHIKI KAISHA;SHIMMA, NOBUO;EBIIKE, HIROSATO;OHWADA, JUN;KAWADA, HATSUO;MORIKAMI, KENJI;NAKAMURA, MITSUAKI;YOSHIDA, MIYUKI;ISHII, NOBUYA;HASEGAWA, MASAMI;YAMAMOTO, SHUN;KOYAMA, KOHEI 发明人 SHIMMA, NOBUO;EBIIKE, HIROSATO;OHWADA, JUN;KAWADA, HATSUO;MORIKAMI, KENJI;NAKAMURA, MITSUAKI;YOSHIDA, MIYUKI;ISHII, NOBUYA;HASEGAWA, MASAMI;YAMAMOTO, SHUN;KOYAMA, KOHEI
分类号 C07D487/04;A61K31/5377;A61P35/00 主分类号 C07D487/04
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