| 摘要 |
<p>The present invention provides an antiretroviral solid oral composition c omprising one or more antiretroviral drugs, for example protease inhibitors such as lopinavir, ritonavir or a combination thereof with one or more excip ients. The invention provides a composition which is smaller for a given amo unt of said active substance and possesses taste masking property and a proc ess for preparing the composition. The present invention also provides an an tiretroviral solid oral composition comprising one or more antiretroviral dr ugs, for example protease inhibitors such as lopinavir, ritonavir or a combi nation thereof with at least one water insoluble polymer, wherein the ratio of drug to polymer in the composition ranges from about 1 :1 to about 1 :6, and a process for preparing the composition.</p> |
