| 发明名称 |
METHODS FOR FRACTIONATION-BASED CHEMICAL ANALYSES |
| 摘要 |
A method (100) for performing chemical analyses includes digesting a reference sample to obtain precursors associated with a peptide in the sample (110), separating the precursors to determine values associated with retention times of the separated precursors (120), ionizing the separated precursors to form precursor ions (130), mass analyzing the precursor ions to determine values associated with mass and with ion intensity (140), and storing a <fcfile of the polypeptide defined by the determined values (150). A subject sample is analyzed (160), and the polypeptide is detected in the subject sample in response to a match between subject-sample and profile values. An apparatus (900) for performing chemical analyses includes a chromatography module (904), a mass-spectrometry module (912), and a computer module (926). |
| 申请公布号 |
EP1886134(A1) |
申请公布日期 |
2008.02.13 |
| 申请号 |
EP20060760687 |
申请日期 |
2006.06.05 |
| 申请人 |
WATERS INVESTMENTS LIMITED |
发明人 |
GORENSTEIN, MARC, V.;GEROMANOS, SCOTT, J.;SILVA, JEFFREY, CRUZ;LI, GUO-ZHONG |
| 分类号 |
G01N30/88;G01N30/72;G01N30/86 |
主分类号 |
G01N30/88 |
| 代理机构 |
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