发明名称 |
Nucleic acid encoding GAD65 |
摘要 |
The invention provides cDNA molecules comprising a part of the cDNA sequence of GAD<SUB>65 </SUB>which encode at least one epitope for autoantibodies to GAD<SUB>65</SUB>. The invention also provides cloning vehicles capable of replication and expression comprising cDNA molecules coding for GAD<SUB>65</SUB>. The invention further provides for hosts transformed with a vehicle having a cDNA molecule coding for GAD<SUB>65</SUB>. In another embodiment, the invention provides for the detection of autoantibodies to GAD<SUB>65 </SUB>using the GAD<SUB>65 </SUB>polypeptides coded for by the cDNA molecules of the invention.
|
申请公布号 |
US7329511(B2) |
申请公布日期 |
2008.02.12 |
申请号 |
US20030641149 |
申请日期 |
2003.08.15 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
TOBIN ALLAN J.;ERLANDER MARK G.;KAUFMAN DANIEL L. |
分类号 |
C12P21/06;A61K38/00;A61K38/51;A61K51/00;A61P3/10;A61P21/02;A61P37/02;C12N1/21;C12N9/88;C12N11/00;C12N15/09;C12N15/60;C12Q1/527;C12Q1/68;C12R1/01;G01N33/53;G01N33/564;G01N33/573 |
主分类号 |
C12P21/06 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|