CELLULAR RECEPTOR FOR ANTIPROLIFERATIVE FACTOR

摘要

The present invention concerns the receptor for antiproliferative factor (APF) from bladder epithelial cells. In particular, there are compositions a nd methods for modulating APF, APF receptor, and/or the binding of APF to AP F receptor. Agents that interfere with the binding of APF to its receptor or agents that enhance the binding of APF to its receptor are contemplated. In specific aspects, certain compositions are employed for a therapeutic purpo se, such as interstitial cystitis or cancer, for example.