Disclosed herein are pyrazole glucokinase activators of the formula (I) w herein R1 to R4 are as defined in the specification and claims, useful for t he treatment of metabolic diseases and disorders, preferably diabetes mellit us.
申请公布号
CA2657566(A1)
申请公布日期
2008.01.31
申请号
CA20072657566
申请日期
2007.07.16
申请人
F. HOFFMANN-LA ROCHE AG
发明人
BERTHEL, STEVEN JOSEPH;RUEBSAM, FRANK;PRINS, THOMAS JAY;MURPHY, DOUGLAS ERIC;KESTER, ROBERT FRANCIS;VOURLOUMIS, DIONISIOS;TRAN, CHINH VIET;SARABU, RAMAKANTH
