Substituted alkyl amido piperidines

摘要

Disclosed is a compound of formula (I) wherein: each R1 is independently hydrogen; -F; -CI; -Br; -I; -CN; -NO2; straight chained or branched C1-C7 alkyl, monofluoroalkyl or polyfluoroalkyl; straight chained or branched C2-C7 alkenyl; C3-C7 cycloalkyl or C5-C7 cycloalkenyl; aryl; heteroaryl; -N(R5)2; -(CH2)mOR5; -COR5; -CO2 R5; -OCOR5; -CON(R5)2; -N(R5)COR5; -N(R5)CON(R5)2; -OCON(R5)2 or -N(R5)CO2R5; R2 and R3 together be -( CH2)p-; R4 is straight chained or branched C1-C7 alkyl, monofluoroalkyl or polyfluoroalkyl, C3-C6 cycloalkyl, C1-C7 alkyl-C3-C5 cycloalkyl; -N(R5) 2 or -( CH2)mOR5; each R5 is independently hydrogen; aryl; heteroaryl or straight chained or branched C1-C7 alkyl, wherein the alkyl may be substituted with an aryl or heteroaryl; R6 is independently hydrogen; straight chained or branched C1-C7 alkyl; R7 is independently hydrogen; phenyl or straight chained or branched C1-C7 alkyl, wherein the alkyl may be substituted with a phenyl; X is independently CR1 or N, provided that if one X is N then the remaining X are CR1; and the remainder of the substituents are as described in the specification; or a pharmaceutically acceptable salt thereof. Also disclosed is the use of the above compound in the manufacture of medicament for treating an affective disorder, a urinary disorder or an eating disorder.