发明名称 |
IMMUNOGENIC COMPOUNDS AND PROTEIN MIMICS |
摘要 |
The invention provides means and methods for inducing and/or enhancing im munogenic reproducibility and/or immunogenicity of a compound, comprising at least in part restricting the conformation of said compound. The conformati on is preferably restricted by the formation of at least one internal bond w ithin said compound. Protein mimics comprising an amino acid sequence bound to a scaffold and/or a carrier, wherein said amino acid sequence comprises a t least one internal SS-bridge, are also herewith provided.
|
申请公布号 |
CA2659225(A1) |
申请公布日期 |
2008.01.31 |
申请号 |
CA20072659225 |
申请日期 |
2007.07.26 |
申请人 |
PEPSCAN SYSTEMS B.V. |
发明人 |
TIMMERMAN, PETER;MELOEN, ROBBERT HANS;PUIJK, WOUTER CORNELIS |
分类号 |
G01N33/68;A61K39/00;A61K47/42;C07K1/04;C07K7/54;C07K14/48;C07K14/49;C07K14/495;C07K14/52;C07K14/59;C07K14/61 |
主分类号 |
G01N33/68 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|