发明名称 |
SUBSTITUTED HETEROCYCLES AND THEIR USE AS CHK1, PDK1 AND PAK INHIBITORS |
摘要 |
This invention relates to novel compounds of Formula (I) and to their pharmaceutical compositions and to their methods of use. These novel compounds possess CHK1 kinase inhibitory activity, PDK1 inhibitory activity and Pak kinase inhibitory activity and are accordingly useful in the treatment and/or prophylaxis of cancer.
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申请公布号 |
KR20080009200(A) |
申请公布日期 |
2008.01.25 |
申请号 |
KR20077025794 |
申请日期 |
2007.11.06 |
申请人 |
ASTRAZENECA AB |
发明人 |
DALY KEVIN;HERON NICOLA;HIRD ALEXANDER;IOANNIDIS STEPHANOS;JANETKA JAMES WALTER;LYNE PAUL;SCOTT JAMIE;TOADER DORIN;VASBINDER MELISSA;YU DINGWEI;YU YAN |
分类号 |
C07D495/04;A61K31/4365 |
主分类号 |
C07D495/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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