发明名称 |
Attenuation of Cytomegalovirus Virulence |
摘要 |
A method is provided for attenuating a cytomegalovirus comprising functionally disrupting an open reading frame of a Toledo genome region or its homolog and making chimeric CMV virus genomes.
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申请公布号 |
US2008019945(A1) |
申请公布日期 |
2008.01.24 |
申请号 |
US20060613501 |
申请日期 |
2006.12.20 |
申请人 |
MEDLMMUNE VACCINES, INC. |
发明人 |
KEMBLE GEORGE;DUKE GREGORY M.;SPAETE RICHARD |
分类号 |
A61K48/00;A61P31/12;C12N7/08 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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