发明名称 |
Aryl-substituted pyridylalkane, alkene, and alkine carboxamides useful as cytostatic useful as cytostatic and immuosuppressive agents |
摘要 |
The invention relates to new pyridylalkane, alkene, and alkine acid amides substituted with an aryl and/or heteroaryl residue according to the general formula (I), with a saturated or one or several-fold unsaturated hydrocarbon residue in the carboxylic acid group, methods for the synthesis of these compounds, medicaments containing these and their production as well as their therapeutic use, especially as cytostatic agents and immunosuppressive agents, for example in the treatment or prevention of various types of tumors and control of immune reactions such as autoimmune diseases.
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申请公布号 |
US7320993(B1) |
申请公布日期 |
2008.01.22 |
申请号 |
US20000596086 |
申请日期 |
2000.06.16 |
申请人 |
ASTELLAS DEUTSCHLAND GMBH |
发明人 |
BIEDERMANN ELFI;HASMANN MAX;LOESER ROLAND;RATTEL BENNO;REITER FRIEDEMANN;SCHEIN BARBARA;SEIBEL KLAUS;VOGT KLAUS;WOSIKOWSKI KATJA;SCHEMAINDA ISABEL |
分类号 |
A61K31/44;C07D491/044;A61K9/00;A61K9/02;A61K9/08;A61K9/10;A61K9/12;A61K9/14;A61K9/19;A61K9/22;A61K9/28;A61K9/48;A61K9/70;A61K31/4406;A61K31/4427;A61K31/443;A61K31/4433;A61K31/4436;A61K31/4439;A61K31/444;A61K31/4709;A61K31/473;A61K31/55;A61K31/675;A61K47/06;A61K47/26;A61P31/00;A61P35/00;A61P37/06;C07D211/00;C07D213/00;C07D213/56;C07D401/12;C07D405/12;C07D409/12;C07D409/14;C07D413/12;C07D417/12;C07D471/04;C07D491/04;C07D495/04;C07F9/36 |
主分类号 |
A61K31/44 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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