МИКРОВЫСТУПЫ, ПРОБИВАЮЩИЕ КОЖУ, ИМЕЮЩИЕ СРЕДСТВО РЕГУЛИРОВАНИЯ ГЛУБИНЫ ПРОБИВКИ

摘要

A device comprising of a plurality of microprojections for piercing the outermost layer of skin is provided for increasing transdermal agent flux. The device includes penetration depth limiters for ensuring uniform depth of piercing by the microprojections, thereby preventing over penetration and undesirable bleeding and pain. The microprojections have a length (L1) which is substantially greater than the intended penetration depth (L2). The microprojection penetration depth limiters allow for more uniform penetration for optimum agent delivery or fluid sampling.