发明名称 NOVEL HETEROCYCLIC COMPOUNDS
摘要 A compound of formula (I), wherein R1 and R2 independently are hydrogen, halogen, trifluoromethyl, hydroxy, C1-6-alkyl or C1-6-alkoxy; and R3 is hydrogen or C1-3-alkyl; and A is C1-3-alkylene; and Y is >CH-CH2-, >C=CH-, >CH-O-, >C=N-, >N-CH2- wherein only the underscored atom participates in the ring system, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neurogenic pain or inflammation.
申请公布号 CA2231835(A1) 申请公布日期 1997.03.27
申请号 CA19962231835 申请日期 1996.09.12
申请人 NOVO NORDISK A/S 发明人 MADSEN, PETER;MIKSIK, FRANTISEK;K NIGOVA, OTYLIE;POLIVKA, ZENDEK;OLSEN, UFFE BANG;KOVANDOVA, MARTINA;SINDELAR, KAREL;SILHANKOVA, ALEXANDRA;JORGENSEN, TINE KROGH;HOHLWEG, ROLF;ANDERSEN, KNUD ERIK
分类号 C07D321/12;A61K31/335;A61K31/357;A61K31/4406;A61K31/55;A61P3/08;A61P25/00;A61P29/00;C07D273/00;C07D273/01;C07D405/06;C07D405/12;C07D413/06;(IPC1-7):C07D405/06;A61K31/40;A61K31/44;A61K31/47;A61K31/495;A61K31/535 主分类号 C07D321/12
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