HETEROARYL SULFONAMIDES AND CCR2/CCR9

摘要

Compounds are provided that act as potent antagonists of the CC R2 receptor. Animal testing demonstrates that these compounds are useful for treating inflammation, a hallmark disease for CCR2. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases, and as controls in assays for the identification of CC R2 antagonists.