发明名称 INTERLEUKIN 21 AND TYROSINE KINASE INHIBITOR COMBINATION THERAPY
摘要 <p>The present invention provides methods for use of IL-21 in combination with a tyrosine kinase inhibitor (TKI) in treatment of diseases in which inhibition of phosphorylation via TK inhibition and modulation of immune function play a clinically beneficial role. These diseases include, but are not limited to, cancers, such as renal cell carcinoma and metastatic melanoma.</p>
申请公布号 WO2008008981(A1) 申请公布日期 2008.01.17
申请号 WO2007US73506 申请日期 2007.07.13
申请人 ZYMOGENETICS, INC.;SIVAKUMAR, PALLAVUR, V.;HAUSMAN, DIANA, F.;HUGHES, STEVEN, D.;SIEVERS, ERIC;MILLER, DENNIS, M. 发明人 SIVAKUMAR, PALLAVUR, V.;HAUSMAN, DIANA, F.;HUGHES, STEVEN, D.;SIEVERS, ERIC;MILLER, DENNIS, M.
分类号 A61K38/20;A61K31/404;A61K31/4412;A61P35/00 主分类号 A61K38/20
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