PROCESS FOR PREPARING PARTICLES OF PROTEINACEOUS MATERIAL

摘要

Protein particles are prepared by causing or allowing protein molecules d ispersed in a liquid medium at a concentration of 8mg.mL-1 or greater to rea ct in the presence of a zero-length crosslinker, so as to produce protein pa rticles comprising protein molecules that are covalently bonded together. Th e protein particles may be produced with sizes in the sub-micron range with closely defined sizes and size distributions. The particles have application s in many fields, but are useful inter alia for the delivery of therapeutic agents and other agents, eg imaging contrast agents, to the body.