<p>A process for preparing gabapentin of formula 1, which comprises Formula (I) converting 1-allyl-cyclohexanecarboxaldehyde into 1-allyl-cyclohexanecarbonitrile; ozonizing 1-allyl-cyclohexanecarbonitrile to obtain 1-cyano-cyclohexaneacetaldehyde; acetalizing 1-cyano-cyclohexaneacetaldehyde with a suitable acetalizing agent to give the corresponding acetal and converting the latter into gabapentin.</p>
申请公布号
WO2008004115(A1)
申请公布日期
2008.01.10
申请号
WO2007IB01977
申请日期
2007.06.29
申请人
ZACH SYSTEM S.P.A.;GHELFI, FRANCO;COTARCA, LIVIUS;RONCAGLIA, FABRIZIO;GIOVANETTI, ROBERTO;NICOLI, ANDREA
发明人
GHELFI, FRANCO;COTARCA, LIVIUS;RONCAGLIA, FABRIZIO;GIOVANETTI, ROBERTO;NICOLI, ANDREA
