发明名称 |
Tetracycline repressor regulated oncolytic viruses |
摘要 |
The present invention is directed oncolytic Herpes simplex-l viruses whose replication is controlled using a tetracycline operator/repressor system. The invention also includes DNA sequences used in making the viruses and methods in which these viruses are used in the treatment of cancer patients with solid tumors.
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申请公布号 |
US2008008686(A1) |
申请公布日期 |
2008.01.10 |
申请号 |
US20070822373 |
申请日期 |
2007.07.05 |
申请人 |
THE BRIGHAM AND WOMEN'S HOSPITAL, INC. |
发明人 |
YAO FENG |
分类号 |
A61K48/00;C07H21/04;C12N7/01 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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