发明名称 |
COMPOSITIONS AND METHODS FOR MODULATING IMMUNE RESPONSES |
摘要 |
<p>The present invention provides a newly identified CD28 family member that functions as lymphocyte inhibitory receptor termed pG6b, which is expressed on T cells. Methods and compositions for modulating pG6b-mediated negative signaling and interfering with the interaction of its counter-receptor for t herapeutic, diagnostic, and research purposes are also provided.</p> |
申请公布号 |
CA2652058(A1) |
申请公布日期 |
2008.01.10 |
申请号 |
CA20072652058 |
申请日期 |
2007.05.14 |
申请人 |
ZYMOGENETICS, INC. |
发明人 |
RAMSDELL, FREDERICK J.;LEVIN, STEVEN D.;HEBB, LUANNE;RIXON, MARK W.;TAFT, DAVID W.;JOHNSTON, JANET V.;HOWARD, EDWARD D.;GAO, ZEREN |
分类号 |
C07K16/28;A61K39/395;A61P35/00;A61P37/00;C07K14/705 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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