发明名称 ГЕТЕРОЦИКЛИЧЕСКИЕ ИНГИБИТОРЫ МЕК И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
摘要 Disclosed are compounds of the Formula I and pharmaceutically acceptable salts and prodrugs thereof, wherein R 1 , R 2 , R 7 , R 8 and R 9 , W, X and Y are as defined in the specification. Such compounds are MEK inhibitors and useful in the treatment of hyperproliferative diseases, such as cancer and inflammation, in mammals, and inflammatory conditions. Also disclosed are methods of using such compounds in the treatment of hyperproliferative diseases in mammals and pharmaceutical compositions containing such compounds.
申请公布号 RU2006120948(A) 申请公布日期 2008.01.10
申请号 RU20060120948 申请日期 2004.11.18
申请人 Эррэй БиоФарма Инк. (US) 发明人 МАРЛОУ Элисон Л. (US);УОЛЛЕС Эли (US);СЕО Джеонгбеоб (US);ЛИССИКАТОС Джозеф П. (US);ЯНГ Хонг Вун (US);БЛЕЙК Джим (US)
分类号 A01N33/02;A01N43/42;A01N43/54;A01N43/58;A01N43/60;A01N43/64;A01N43/90;A61K;A61K31/40;A61K31/415;A61K31/416;A61K31/44;A61K31/4439;A61K31/4745;A61K31/495;A61K31/50;A61K31/501;A61K31/502;A61K31/517;A61K31/519;A61K31/53;A61K31/655;C07D;C07D209/44;C07D209/46;C07D213/80;C07D213/82;C07D215/48;C07D221/04;C07D231/56;C07D237/24;C07D237/26;C07D237/28;C07D237/32;C07D239/74;C07D401/04;C07D401/06;C07D403/02;C07D413/02;C07D413/04;C07D413/14;C07D417/02;C07D417/04;C07D471/02;C07D471/04;C07D487/02;C07D491/02;C07D498/02 主分类号 A01N33/02
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