发明名称 NEW NAPHTHALENE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
摘要 A novel naphthalene compound, its enantiomers or its pharmaceutically acceptable addition salt, a method for preparing the compound, and a pharmaceutical composition containing the compound are provided to treat the disorder of melatonin system. A naphthalene compound is represented by the formula I. The compound of the formula I is prepared by treating the compound represented by the formula II with dimethyl carbonate in a basic medium to obtain the compound represented by the formula III; reducing the compound represented by the formula III in the presence of hydrazine to obtain the compound represented by the formula IV; and condensing the compound represented by the formula IV with ethyl fluoroacetate to obtain the compound represented by the formula I.
申请公布号 KR20080003264(A) 申请公布日期 2008.01.07
申请号 KR20070064102 申请日期 2007.06.28
申请人 LES LABORATOIRES SERVIER 发明人 YOUS SAID;PERES BASILE;SABAOUNI AHMED;BERTHELOT PASCAL;SPEDDING MICHAEL;DELAGRANGE PHILIPPE;CAIGNARD DANIEL HENRI;MILLAN MARK
分类号 C07C233/04;C07C233/00 主分类号 C07C233/04
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