发明名称 |
High Molecular Weight Derivatives of Vitamin K-Dependent Polypeptides |
摘要 |
Modifications of vitamin K-dependent polypeptides that lead to enhanced protein function on a weight or molar basis and/or increase of protein lifetime in the circulation are described. Both objectives are important for using vitamin K-dependent polypeptides for pro- and anti-coagulation therapies, as well as for other uses in the circulation.
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申请公布号 |
US2008004221(A1) |
申请公布日期 |
2008.01.03 |
申请号 |
US20070696579 |
申请日期 |
2007.04.04 |
申请人 |
NELSESTUEN GARY L;BACH RONALD;STONE MATTHEW;HARVEY STEPHEN B |
发明人 |
NELSESTUEN GARY L.;BACH RONALD;STONE MATTHEW;HARVEY STEPHEN B. |
分类号 |
A61K38/36;A61K38/00;A61K47/48;A61P7/00;C07K14/745;C12N9/64 |
主分类号 |
A61K38/36 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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