发明名称 CRYSTAL MODIFICATION A OF 8-CYANO-1- CYCLOPROPYL -7-(1S,6S-2, 8-DIAZABICYCLO [4.3.0]NONAN -8-YL)-6- FLUORO-1, 4-DIHYDRO- 4-OXO-3- QUINOLINE CARBOXYLIC ACID
摘要 The present invention relates to a defined crystal modification of 8-cyano-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0] nonan-8-yl)-6-fluoro-1, 4-dihydro-4-oxo-3-quinolinecarboxylic acid of the formula (I), to processes for its preparation and to its use in pharmaceutical preparations.The crystal modification can be distinguished from other crystal modifications of 8-cyano-1-cyclopropyl-7-(1S,6S-2,8-diazabicyclo[4.3.0]nonan-8-yl )-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid of the formula (I) by its characteristic X-ray powder diffractogram and its differential thermodiagram (see description).
申请公布号 PL196085(B1) 申请公布日期 2007.12.31
申请号 PL19990347786 申请日期 1999.11.15
申请人 BAYER AG 发明人 HIMMLER THOMAS;HALLENBACH WERNER;RAST HUBERT
分类号 C07D471/04;A01N43/90;A61K31/4709;A61P31/02;A61P31/04 主分类号 C07D471/04
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