| 发明名称 |
DUAL NK1/NK3 ANTAGONISTS FOR TREATING SCHIZOPHRENIA |
| 摘要 |
<p>The present invention provides a method for the treatment of schizophrenia which comprises administering a compound of formula wherein the substituents are as described herein or a pharmaceutically active acid-addition salt thereof. In particular, the invention provides methods for treating both positive and negative symptoms of schizophrenia through dual inhibition of NK1 and NK3 receptors. The invention also provides novel compounds with formula I and methods for preparing compounds of the invention.</p> |
| 申请公布号 |
SI1643998(T1) |
申请公布日期 |
2007.12.31 |
| 申请号 |
SI20040030471T |
申请日期 |
2004.06.25 |
| 申请人 |
F.HOFFMANN - LA ROCHE AG |
发明人 |
HOFFMANN TORSTEN;KOBLET ANDREAS;PETERS JENS-UWE;SCHNIDER PATRICK;SLEIGHT ANDREW;STADLER HEINZ |
| 分类号 |
A61K31/44;A61K31/4418;A61K31/4427;A61K31/4439;A61K31/444;A61K31/46;A61K31/496;A61K31/4995;A61K31/5377;A61K31/5386;A61K31/541;A61K31/547;A61K31/551;A61K31/554;C07D213/75;C07D401/04;C07D413/04;C07D417/04;C07D419/04;C07D451/04;C07D487/08;C07D491/10;C07D495/10;C07D497/10;C07D498/08;C07D513/08 |
主分类号 |
A61K31/44 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
