发明名称 БЕНЗАННЕЛИРОВАННЫЕ СОЕДИНЕНИЯ В КАЧЕСТВЕ АКТИВАТОРОВ PPAR
摘要 There are presented compounds of the formula wherein R6 and R7 is R4 and R5 or R5 and R6 together with the carbon atoms to which they are attached, form a ring as defined in the description and X1, X2, Y1 to Y4, R1 to R13 and n are as specified in the description, and to all enantiomers and pharmaceutically acceptable salts and/or esters thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are modulated by PPARdelta and/or PPARalpha agonists.
申请公布号 RU2006119508(A) 申请公布日期 2007.12.27
申请号 RU20060119508 申请日期 2004.10.28
申请人 Ф.ХОФФМАНН-ЛЯ РОШ АГ (CH) 发明人 АККЕРМАНН Жан (CH);ЭБИ Иоганнес (CH);БИНДЖЕЛИ Альфред (CH);ГРЕТЕР Уве (DE);ИРТ Жорж (FR);КУН Бернд (CH);МЭРКИ Ханс-Петер (CH);МЕЙЕР Маркус (DE);МОР Петер (CH);РАЙТ Маттью Блейк (CH)
分类号 C07D213/38;C07D213/30;C07D239/26 主分类号 C07D213/38
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