摘要 |
The application relates to compounds of the formula I: or pharmaceuticall y acceptable salts thereof, wherein: m is, from 0 to 3; q is from 0 to 3; Ar is optionally substituted aryl or optionally substituted heteroaryl; R1 and R7 each independently is halo, allkyl, haloalkyl, alkoxy, hydroxy,heteroalk yl, cyano,-S(O)-Ra,-C(=O)-NRbRC,-SO2-NRbRc,-N(Rd)-C(=O)-Re, or -C(=O)-Rf, wh ere t is from 0 to i Ra, Rb, Rc, Rd and Re each independently is hydrogen or alkyl, and Rf is hydrogen, alkyl, alkoxy or hydroxy; (II), n is from 1 to 3 ; The compounds are 5-Hydroxytryptamine 6 and 2A receptor modulators. Also p rovided are methods for preparing, compositions comprising, and methods for using compounds of formula I.
|