发明名称 |
Polyene oxazoles and processes for their preparation |
摘要 |
Polyene oxazoles of the following formula wherein R<SUB>3 </SUB>is selected from H and methyl, are disclosed. Such compounds, and pharmaceutically acceptable salts thereof, may be used in the inhibition of tumor cell growth. The polyene oxazoles and their pharmaceutically acceptable salts may be formulated as pharmaceutical compositions with pharmaceutically acceptable carriers for use in the inhibition of tumor cells. The polyene oxazoles may be obtained from strains of Streptomyces sparsogenes, such as strain 022 having deposit number IDAC 270504-04. |
申请公布号 |
US7312339(B2) |
申请公布日期 |
2007.12.25 |
申请号 |
US20040865767 |
申请日期 |
2004.06.14 |
申请人 |
THALLION PHARMACEUTICALS INC. |
发明人 |
MCALPINE JAMES B.;FARNET CHRIS M.;ZAZOPOULOS EMMANUEL;ISMAIL NARGIS;BACHMANN BRIAN O. |
分类号 |
C07D207/444;A61P35/00;C07D209/48;C07D263/32;C07D413/12;C12P17/14 |
主分类号 |
C07D207/444 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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