This invention provides a diagnostic method for determining statin induced myopathy. The method is especially applicable for determining warnings, early signs and aiso symptomatic myopathy. The method inciudes coilecting a lipidomic profile from a biological sample such as blood or serum and comparing the obtained lipidomic profile to reference iipidomic markers. The reference iipidomic markers have been established by combining a pro-inflammatory muscle tissue gene expression profile with a iipidomic profile associated with high dosage statin treatment. This invention aiso relates to a kit for performing a method for determining statin induced myopathy.
申请公布号
WO2007144467(A1)
申请公布日期
2007.12.21
申请号
WO2007FI50344
申请日期
2007.06.12
申请人
ZORA BIOSCIENCES OY;LAAKSONEN, REIJO;ORESIC, MATEJ;LEHTIMAEKI, TERHO;PAEIVAE, HANNU
发明人
LAAKSONEN, REIJO;ORESIC, MATEJ;LEHTIMAEKI, TERHO;PAEIVAE, HANNU