发明名称 Derivatives Of Chemotherapeutic Agents With A Formaldehyde Releasing Moiety
摘要 Novel conjugates of chemotherapeutic agents, which are designed so as to release formaldehyde or analogs thereof upon cleavage, processes of preparing same, pharmaceutical compositions containing same and methods utilizing same for treating medical conditions such as cancer, immune-mediated diseases, viral infections and diseases, bacterial infections and diseases, fungal infections and diseases, protozal infections and diseases and more, and particularly for treating such conditions which are characterized by drug resistance are provided.
申请公布号 US2007293517(A1) 申请公布日期 2007.12.20
申请号 US20060597829 申请日期 2006.11.28
申请人 RAMOT AT TEL AVIV UNIVERSITY LTD. 发明人 NUDELMAN ABRAHAM;REPHAELI ADA
分类号 A61K31/513;A61K31/45;A61K31/454;A61K31/506;A61K31/522;A61K47/48;A61P31/00;A61P31/04;A61P31/10;A61P31/12;A61P35/00;A61P37/00;C07D239/553;C07D401/04;C07D473/38 主分类号 A61K31/513
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