发明名称 USE OF A COMBINATION COMPRISING A2A ADENOSINE RECEPTOR AGONISTS AND ANTI-PATHOGENIC AGENTS FOR THE TREATMENT OF INFLAMMATORY DISEASES
摘要 The present invention provides a therapeutic method for treating biological diseases that includes the administration of an effective amount of a suitable antibiotic agent, antifungal agent or antiviral agent in conjunction with an A2A adenosine receptor agonist. If no anti-pathogenic agent is known the A2A agonist can be used alone to reduce inflammation, as may occur during infection with antibiotic resistant bacteria, or certain viruses such as those that cause SARS or Ebola. Optionally, the method includes administration of a type IV PDE inhibitor.
申请公布号 EP1496911(B1) 申请公布日期 2007.12.19
申请号 EP20030728372 申请日期 2003.04.10
申请人 UNIVERSITY OF VIRGINIA PATENT FOUNDATION 发明人 LINDEN, JOEL, M.;SULLIVAN, GAIL, W.;MACDONALD, TIMOTHY, L.;SCHELD, W. MICHAEL;OBRIG, TOM G.;RIEGER, JAYSON M.
分类号 A61K31/52;A61P29/00;C07H19/16 主分类号 A61K31/52
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