发明名称 |
Novel compounds, isomer thereof or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist; and a pharmaceutical composition containing the same |
摘要 |
This present invention relates to compounds of formula (I), in which R 3 represents C2-C5 alkenyl or C2-C5 alkynyl and the other variables are as defined in the claims, isomers thereof or pharmaceutically acceptable salts thereof as vanilloid receptor (Vanilloid Receptor 1; VR1; TRPV1) antagonists; and a pharmaceutical composition containing the same.
The present invention provides a pharmaceutical composition for preventing or treating pain, inflammatory disease of the joints, urinary bladder hypersensitivity including urinary incontinence, stomach duodenal ulcer, irritable bowel syndrome, inflammatory bowel disease, neurotic/allergic/inflammatory skin disease, psoriasis, asthma, chronic obstructive pulmonary disease, pruritus or prurigo.
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申请公布号 |
EP1862454(A1) |
申请公布日期 |
2007.12.05 |
申请号 |
EP20060011490 |
申请日期 |
2006.06.02 |
申请人 |
AMOREPACIFIC CORPORATION |
发明人 |
KIM, HEE-DOO;SUH, YOUNG-GER;PARK, HYEUNG-GEUN;OH, UH TAEK;PARK, YOUNG -HO;SHIN, SONG SEOK;LEE, KI-WHA;KIM, SUN-YOUNG;KIM, JIN KWAN;JEONG, YEON SU;WOO, BYOUNG YOUNG |
分类号 |
A61K31/18;C07C335/12;A61P29/00 |
主分类号 |
A61K31/18 |
代理机构 |
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地址 |
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