| 摘要 |
<p>Disclosed is a compound of formula I, wherein W is NR4, O or S, X is O, S, SO, SO2 or NR17, and the remaining substituents are as defined in the specification. The compounds show good binding to the ORL1 receptor and are useful in the treatment of pain.</p> |
| 申请人 |
GRUNENTHAL GMBH |
发明人 |
HINZE, CLAUDIA;AULENBACHER, OTTO;SUNDERMANN, BERND;OBERBORSCH, STEFAN;FRIDERICHS, ELMAR;ENGLBERGER, WERNER;KOGEL, BABETTE-YVONNE;LINZ, KLAUS;SCHICK, HANS;SONNENSCHEIN, HELMUT;HENKEL, BIRGITTA;ROSE, VALERIE SARAH;LIPKIN, MICHAEL JONATHAN |
