发明名称 |
COMPOSITION FOR DIAGNOSING AMYLOID-RELATED DISEASE |
摘要 |
<p>It is intended to provide a composition which contains a compound represented by the following general formula (I): wherein R<SUP>1</SUP> represents 5-iodothiophen-2-yl, etc.; and R<SUP>2</SUP> represents 4-dimethylaminophenyl, etc. Because of having a high specificity of binding to amyloid ß-protein, a high blood-brain-barrier permeability and an ability to quickly disappear from parts other than a senile plaque in the brain, the above compound is useful in diagnosing an amyloid-related disease such as Alzheimer's disease.</p> |
申请公布号 |
WO2007136059(A1) |
申请公布日期 |
2007.11.29 |
申请号 |
WO2007JP60436 |
申请日期 |
2007.05.22 |
申请人 |
NAGASAKI UNIVERSITY;MORI, HIROSHI;NAKAYAMA, MORIO;HARATAKE, MAMORU;ONO, MASAHIRO |
发明人 |
MORI, HIROSHI;NAKAYAMA, MORIO;HARATAKE, MAMORU;ONO, MASAHIRO |
分类号 |
A61K51/00;C07D213/61;C07D233/64;C07D277/24;C07D307/42;C07D333/28;C07D333/36;C07D409/06 |
主分类号 |
A61K51/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|