发明名称 COMPOSITION FOR DIAGNOSING AMYLOID-RELATED DISEASE
摘要 <p>It is intended to provide a composition which contains a compound represented by the following general formula (I): wherein R&lt;SUP&gt;1&lt;/SUP&gt; represents 5-iodothiophen-2-yl, etc.; and R&lt;SUP&gt;2&lt;/SUP&gt; represents 4-dimethylaminophenyl, etc. Because of having a high specificity of binding to amyloid ß-protein, a high blood-brain-barrier permeability and an ability to quickly disappear from parts other than a senile plaque in the brain, the above compound is useful in diagnosing an amyloid-related disease such as Alzheimer's disease.</p>
申请公布号 WO2007136059(A1) 申请公布日期 2007.11.29
申请号 WO2007JP60436 申请日期 2007.05.22
申请人 NAGASAKI UNIVERSITY;MORI, HIROSHI;NAKAYAMA, MORIO;HARATAKE, MAMORU;ONO, MASAHIRO 发明人 MORI, HIROSHI;NAKAYAMA, MORIO;HARATAKE, MAMORU;ONO, MASAHIRO
分类号 A61K51/00;C07D213/61;C07D233/64;C07D277/24;C07D307/42;C07D333/28;C07D333/36;C07D409/06 主分类号 A61K51/00
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