| 发明名称 |
LLO-ENCODING DNA/NUCLEIC ACID VACCINES AND METHODS COMPRISING SAME |
| 摘要 |
The present invention provides vaccines, compositions, and recombinant vectors comprising a gene or mRNA encoding an N-terminal fragment of an LLO protein and an antigen, either fused together or encoded separately, and provides methods of invoking CD4<SUP>+</SUP> and/or CD8<SUP>+</SUP> T cell-mediated immune responses against an antigen and impeding the growth of or shrinking tumors, comprising same. |
| 申请公布号 |
WO2007059030(A3) |
申请公布日期 |
2007.11.29 |
| 申请号 |
WO2006US43987 |
申请日期 |
2006.11.13 |
| 申请人 |
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA;PATERSON, YVONNE;TREML, JOHN;PENG, XIAOHUI |
发明人 |
PATERSON, YVONNE;TREML, JOHN;PENG, XIAOHUI |
| 分类号 |
A61K48/00;C12N15/63 |
主分类号 |
A61K48/00 |
| 代理机构 |
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