Lrp4/Corin DOPAMINE-PRODUCING NEURON PRECURSOR CELL MARKER

摘要

PROBLEM TO BE SOLVED: To provide an efficient method for separating dopamine-producing neuron precursor cells.

SOLUTION: The polynucleotide probe and antibody for detecting an Lrp4/Corin dopamine-producing neuron precursor cell marker, and a method for selecting the precursor cells by using the same are provided. By using the expression of the Lrp4 in the cells as an index, it becomes possible to select suitable cells for the transplantation treatment of neurodegenerative diseases including Parkinson disease even in points of safety, survival rate and network formation ability.

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