发明名称 Treatment of tumors expressing mutant EGF receptors
摘要 The invention discloses methods of treatment of tumors that express oncogenic forms of the epidermal growth factor receptor (EGFR), such as EGFRvIII. The methods include testing of cancer patients for expression of EGFRvIII in their tumors, followed by treatment with a protein that contains antibody variable regions that recognize specific epitopes on the surface of the EGFR.
申请公布号 US2007274991(A1) 申请公布日期 2007.11.29
申请号 US20070729483 申请日期 2007.03.29
申请人 发明人 WAY JEFFREY C.;CHAO GINGER;CRESSON CATHERINE;LAUFFENBURGER DOUGLAS;WITTRUP K. D.
分类号 A61K39/395 主分类号 A61K39/395
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