The present invention provides a novel imaging agent targeting the mannose-6-phosphate (M6P) receptor suitable for the non-invasive visualization of fibrosis. A method for the preparation of the imaging agent is also provided by the invention, as well as a precursor for use in said method. The invention also provides a pharmaceutical composition comprising the imaging agent and a kit for the preparation of the pharmaceutical composition. In a further aspect, use of the imaging agent for in vivo imaging and in the preparation of a medicament for the diagnosis of a condition in which the mannose-6-phosphate receptor is upregulated is provided.
申请公布号
WO2007066115(A3)
申请公布日期
2007.11.29
申请号
WO2006GB04575
申请日期
2006.12.07
申请人
GE HEALTHCARE LIMITED;CHETTIBI, SALAH;NEWTON, BEN;GUILBERT, BENEDICTE;TOLLESHAUG, HELGE;SOLBAKKEN, MAGNE