摘要 |
The invention provides a process for the chromatographic purification of Tacrolimus, using a silver modified sorbent, selected from the group consisting of silver modified aluminum oxide, zirconium oxide, styrene divinylbenzene copolymer, adsorption resin, cation exchange resin, anion exchange resin, reverse phase silica gel, and cyano silica-gel, and separating the Tacrolimus chromatographically with the silver modified sorbent as a stationary phase.
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申请人 |
TEVA GYOGYSZERGYAR ZARTKORUEN MUKODO;IVAX PHARMACEUTICALS S.R.O.;TEVA PHARMACEUTICALS USA, INC.;CVAK, LADISLAV;BUCHTA, MARTIN;JEGOROV, ALEXANDR;BLATNY, PAVEL;KERI, VILMOS;CSORVASI, ANDREA;SIMON, ANGELA;MAKO, GYORGYNE |
发明人 |
CVAK, LADISLAV;BUCHTA, MARTIN;JEGOROV, ALEXANDR;BLATNY, PAVEL;KERI, VILMOS;CSORVASI, ANDREA;SIMON, ANGELA;MAKO, GYORGYNE |