PURE BIOLOGICALLY ACTIVE COLISTIN, ITS COMPONENT AND COLISTIN FORMULATION FOR TREATMENT OF PULMONARY INFECTION

摘要

PROBLEM TO BE SOLVED: To provide a pure biologically active colistin, its component, and a colistin formulation for the treatment of pulmonary infection. SOLUTION: The pure biologically active colistin, all its components, a given mixture thereof or a pharmaceutically acceptable salt thereof and an aerosol formulation containing the substantially pure biologically active colistin, any of its biologically active components, a mixture thereof or a pharmaceutically acceptable salt thereof are provided. The formulation is suitable for atomization, and an atomized form offers an effective treatment and prevention of Pseudomonas aeruginosa infection or other susceptible pulmonary infections (e.g. Stenotrophomonas maltophilia). COPYRIGHT: (C)2008,JPO&INPIT