POTENTIATOR FOR RADIATION THERAPY COMPRISING PYRIDINE DERIVATIVE AS ACTIVE INGREDIENT.

摘要

Disclosed is a potentiator for radiation therapy which can be used in combination with cancer radiation therapy to increase the radiation dose and can also reduce adverse side effects of the radiation therapy. A potentiator for radiation therapy comprising, as the active ingredient, a pyridine derivative represented by the general formula (1): (1) wherein R¹, R² and R⁴ independently represent a hydrogen atom, a hydroxyl group or a protected hydroxyl group, provided that all of R¹, R² and R⁴ are not a hydrogen atom; R³ represents a halogen atom, an amino group, a carboxyl group, a carbamoyl group, a cyano group, a nitro group, an alkyl group having 1 to 6 carbon atoms, an alkenyl group having 2 to 6 carbon atoms or a carbonyl group having an alkoxy group having 1 to 6 carbon atoms.