| 发明名称 |
SUBSTITUTED ARYLAMINE COMPOUNDS AND THEIR USE AS 5-HT6 MODULATORS |
| 摘要 |
The invention relates to 5-HT6 receptor antagonists. Novel arylamine compounds and use of these compounds and their pharmaceutical compositions, e.g., in the treatment, modulation and/or prevention of physiological conditions associated with serotonin action, such as in treating obesity, and obesity-related disorders, e.g., cardiovascular disease, digestive disease, respiratory disease, cancer and type II diabetes; and psychological disorders such as schizophrenia, are disclosed. |
| 申请公布号 |
EP1856075(A1) |
申请公布日期 |
2007.11.21 |
| 申请号 |
EP20060719542 |
申请日期 |
2006.01.25 |
| 申请人 |
EPIX DELAWARE, INC. |
发明人 |
BECKER, OREN;LOBERA, MERCEDES;MELENDEZ, ROSA E.;SHARADENDU, ANURAG;WU, LAURENCE;YU, XIANG, Y.;DHANOA, DALE S.;CHERUKU, SRINIVASA, RAO;MARANTZ, YAEL;NOIMAN, SILVIA;FICHMAN, MERAV;SENDEROWITZ, HANOCH;SHACHAM, SHARON;SAHA, ASHIS;ORBACH, PINI |
| 分类号 |
C07D295/12;A61K31/495;A61K31/496;C07D243/08;C07D311/68;C07D317/62;C07D319/18;C07D333/66 |
主分类号 |
C07D295/12 |
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