| 摘要 |
FIELD: chemistry. ^ SUBSTANCE: invention relates to organic chemistry, specifically to a method of producing 2,3,4,5-tetraalkylthiophenes, which can be used as an intermediate product during synthesis of dyes, biologically active compounds, as well as components of flavour boosters in food, additives to oil and hydraulic fluids. A method is described for producing 2,3,4,5-tetraalkylthiophenes, involving reaction of disubstituted acetylenes with n-BuMgCl in the presence of a zirconocene dichloride catalyst in an argon atmosphere at room temperature in diethyl ether for 2-4 hours with subsequent addition of elemental sulphur S8 in equimolar amount with respect to BuMgCl and boiling in benzene for 5 hours. ^ EFFECT: obtaining end product with high selectivity using simple technique due to exclusion of difficult to access 1,4-butadiene diiodide, highly pyrophoric n-butylithium and highly toxic carbon disulphide. ^ 1 cl, 1 tbl, 9 ex |
