发明名称 ИНГИБИТОРЫ СЕРИНОВЫХ ПРОТЕАЗ, ОСОБЕННО HCV NS3-NS4A ПРОТЕАЗЫ
摘要 The present invention relates to compounds of formula: (I) or a pharmaceutically acceptable salt or mixtures thereof that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease. As such, they act by interfering with the life cycle of the hepatitis C virus and are also useful as antiviral agents. The invention further relates to compositions comprising these compounds either for ex vivo use or for administration to a patient suffering from HCV infection and to processes for preparing the compounds. The invention also relates to methods of treating an HCV infection in a patient by administering a composition comprising a compound of this invention. The invention further relates to processes for preparing theses compounds.
申请公布号 RU2006115558(A) 申请公布日期 2007.11.20
申请号 RU20060115558 申请日期 2004.10.08
申请人 ВЕРТЕКС ФАРМАСЬЮТИКАЛЗ ИНКОРПОРЕЙТЕД (US) 发明人 КОТТРЕЛЛ Кевин М. (US);ПЕРНИ Роберт Б. (US);ПИТЛИК Янош (US)
分类号 C07K5/10;A61K38/05;A61K38/07;A61K38/08;C07K5/06;C07K5/08;C07K7/06 主分类号 C07K5/10
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