发明名称 |
IMPROVED COMPOSITIONS AND METHODS OF TESTING FOR TUBERCULOSIS AND MYCOBACTERIUM INFECTION |
摘要 |
<p>The present disclosure concerns methods, compositions and apparatus for detecting pathogens and/or molecular markers. In a particular embodiment, the pathogen to be detected may be Mycobacterium bovis or any other Mycobacterium species that causes tuberculosis in a mammal. However, the disclosed methods are not limited and virtually any type of pathogen and/or molecular marker may be screened and detected. Preferred embodiments comprise reflex supplemental testing using the same assay at approximately 100% sensitivity and the highest possible corresponding sensitivity - in one example 70%. Such assay conditions, used iteratively, result in elimination of 70% of uninfected subjects for each round of testing. Use of 4 or more rounds of testing results in less than 1% error. Since only positive samples are retested, the methods provide a rapid, inexpensive and highly accurate way to detect infected subjects.</p> |
申请公布号 |
WO2007130846(A2) |
申请公布日期 |
2007.11.15 |
申请号 |
WO2007US67564 |
申请日期 |
2007.04.26 |
申请人 |
SHERWOOD, ANNE L.;PRITEST, INC.;GREEN, LAWRENCE |
发明人 |
GREEN, LAWRENCE;SHERWOOD, ANNE L. |
分类号 |
G01N33/569 |
主分类号 |
G01N33/569 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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