PHENYL-SUBSTITUTED ALKENYLCARBOGUANIDIDES CARRYING PERFLUOROALKYL GROUPS, A PROCESS FOR THEIR PREPARATION, THEIR USE AS A MEDICAMENT OR DIAGNOSTIC AGENT, AND ALSO A MEDICAMENT CONTAINING THEM

摘要

Phenyl-substituted alkenylcarboguanidides carrying perfluoroalkyl groups, of the formula I (see Formula I) in which the substituents have the meanings stated in the description, and their pharmaceutically suitable salts, are described. They are obtained by reacting a compound II (see Formula II) with guanidine, in which R(1) to R(5) and R(A), R(B), R(C) and R(D) have the stated meaning, and L is a leaving group which easily undergoes nucleophilic substitution. Compounds I are excellent cardiovascular therapeutic agents.