| 发明名称 |
PHARMACEUTICAL COMBINATIONS |
| 摘要 |
The invention provides a combination for use as a protein kinase B inhibitor, the combination comprising (or consisting essentially of) an ancillary compound and: (I) a compound of the formula: or salts, solvates, tautomers or N-oxides thereof, wherein R<SUP>1</SUP>, Q<SUP>1</SUP>, Q<SUP>2</SUP>, E, G, T, R<SUP>4</SUP>, J<SUP>1</SUP> and J<SUP>2</SUP> are as defined in the claims; or (II) a compound having the formula (I): or salts, solvates, tautomers or N-oxides thereof, wherein R<SUP>1</SUP>, R<SUP>2</SUP>, R<SUP>3</SUP>, R<SUP>4</SUP>, E, A, T, J<SUP>1</SUP> and J<SUP>2</SUP> are as defined in the claims. |
| 申请公布号 |
WO2007125310(A2) |
申请公布日期 |
2007.11.08 |
| 申请号 |
WO2007GB01502 |
申请日期 |
2007.04.25 |
| 申请人 |
ASTEX THERAPEUTICS LIMITED;THE INSTITUTE OF CANCER RESEARCH:ROYAL CANCER HOSPITAL;CANCER RESEARCH TECHNOLOGY LIMITED;THOMPSON, NEIL, THOMAS;LYONS, JOHN, FRANCIS;BOYLE, ROBERT, GEORGE;GRIMSHAW, KYLA, MERRIOM;GARRETT, MICHELLE, DAWN;COLLINS, IAN |
发明人 |
THOMPSON, NEIL, THOMAS;LYONS, JOHN, FRANCIS;BOYLE, ROBERT, GEORGE;GRIMSHAW, KYLA, MERRIOM;GARRETT, MICHELLE, DAWN;COLLINS, IAN |
| 分类号 |
A61K31/52;A61K45/06;A61P35/00;A61P43/00 |
主分类号 |
A61K31/52 |
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