发明名称 |
Methods and sequences to suppress primate huntington gene expression in vivo |
摘要 |
Disclosed herein are sequences, molecules and methods used to suppress the expression of HD genes encoding for huntingtin protein in primates including Macaca mulatta and Homo sapiens. These sequences, molecules and methods aid in the study of the pathogenesis of HD and can also provide a treatment for this disease by reducing HD mRNA without causing death, locomotor impairment or cellular alterations of the Macaca mulatta and Homo sapiens.
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申请公布号 |
US2007261126(A1) |
申请公布日期 |
2007.11.08 |
申请号 |
US20060501634 |
申请日期 |
2006.08.09 |
申请人 |
KAEMMERER WILLIAM F;KAYTOR MICHAEL D |
发明人 |
KAEMMERER WILLIAM F.;KAYTOR MICHAEL D. |
分类号 |
A01K67/027;A61K48/00;C07H21/04;C12N15/86 |
主分类号 |
A01K67/027 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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