| 发明名称 |
Anti-Tumor Activity of an Oncolytic Adenovirus-Delivered Oncogene siRNA |
| 摘要 |
The present invention includes compositions and methods for the knockdown of one or more genes to a target cell in need of gene therapy by using an siRNA transgene that is integrated into a replication-competent, oncolytic adenovirus.
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| 申请公布号 |
US2007258952(A1) |
申请公布日期 |
2007.11.08 |
| 申请号 |
US20070744236 |
申请日期 |
2007.05.04 |
| 申请人 |
BAYLOR RESEARCH INSTITUTE;MUREX PHARMACEUTICALS;BAYLOR UNIVERSITY |
发明人 |
TONG ALEX W.;ZHANG YU AN;NEMUNAITIS JOHN J.;SHEN YUQIAO;CHEN PO-HSUN;SAMUEL SHIRLEY K. |
| 分类号 |
A61K48/00;C12N15/861 |
主分类号 |
A61K48/00 |
| 代理机构 |
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